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A New Way to Image Myelin

Scientists combine particle physics and neuroscience to visualize a key element of the nervous system.

Researchers who study myelin have long had to choose between imaging the substance with noninvasive but indirect methods that are challenging to interpret and direct but invasive methods that destroy the imaged sample in the process. Now, scientists propose a new and non-destructive way to image myelin.

To learn about how the new technique works and what inspired it, open the visual story in full screen or view the embedded version below.

Related Publication

Georgiadis M, Schroeter A, Gao Z, Guizar-Sicairos M, Liebi M, Leuze C, McNab JA, Balolia A, Veraart J, Ades-Aron B, Kim S, Shepherd T, Lee CH, Walczak P, Chodankar S, DiGiacomo P, David G, Augath M, Zerbi V, Sommer S, Rajkovic I, Weiss T, Bunk O, Yang L, Zhang J, Novikov DS, Zeineh M, Fieremans E, Rudin M.
Nanostructure-specific X-ray tomography reveals myelin levels, integrity and axon orientations in mouse and human nervous tissue.
Nat Commun. 2021 May 19;12(1):2941. doi: 10.1038/s41467-021-22719-7