Collaborative Projects

CAI²R works with partners across the U.S. and abroad to accelerate the development of high-impact biomedical imaging technologies.

We are engaged in 67 Collaborative Projects with researchers at 33 institutions in nine countries on four continents.

Collaborative Projects (CPs) are joint investigations with scientists and clinicians in the U.S. and abroad that serve as test-beds for new technologies with significant potential biomedical impact.

Through CPs we engage research partners in “push-pull” relationships. The technologies provided by our Center help investigators solve uniquely challenging problems (push). In return, feedback from CP partners helps us modify and improve the very technologies we develop (pull).

Most CPs can be classified as focused on musculoskeletal, neurologic, oncologic, or cardiovascular imaging applications. Some CPs are better understood as industry partnerships aimed at technological development per se. All CPs interact with at least one of our Center’s Technology R&D Projects (TR&Ds). A few also interact with our Training and Dissemination components (T&D), where dissemination means open sharing of unique research resources and provision of advanced capabilities via Service Projects.

Jump to:

• Proposed Collaborative Projects
• Active Collaborative Projects
• Concluded Collaborative Projects
• Contact

Proposed Collaborative Projects

Collaborative projects put forth in our NCBIB’s renewal proposal for the 2024-2029 funding period accelerate the development of our newest technologies while advancing our partners’ scientific investigations.

Geographic Distribution of Proposed Projects

Taken together, our proposed Collaborative and Service Projects involve research partners at more than 40 institutions in 13 states and 10 countries across North America, Europe, Asia, and Australia.

Interactions of Proposed Collaborative Projects

TR&Ds →	1	2	3
CP 1 [CP Huang-Lee-Rosen] neuro		●	●
CP 2 [CP Ugurbil-Metzger] neuro		●
CP 3 [CP Northington] neuro			●
CP 4 [CP Liu] MSK	●
CP 5 [CP Srinivasan] neuro		●
CP 6 [CP Jelescu] neuro			●
CP 7 [CP Edelman] neuro, onco	●
CP 8 [CP Yin] abdominal	●
CP 9 [CP Otazo] onco	●	●
CP 10 [CP Sierra] neuro			●
Collaborative Projects 11-32	●	●	●

List of Proposed Collaborative Projects

• Revealing tissue microstructure on a Connectome 2.0 scanner

  🇺🇸 Massachusetts General Hospital, Boston, MA

  Susie Yi Huang, MD, PhD; Hong-Hsi Lee, PhD; Bruce Rosen, MD, PhD

  TR&D 2, TR&D 3

  neurologic imaging
• Technology to realize the full potential of ultra-high-field MRI

  🇺🇸 University of Minnesota, Minneapolis, MN

  Kamil Ugurbil, PhD; Gregory Metzger, PhD

  TR&D 2

  neurologic imaging
• Imaging neonatal hypoxic ischemic injury

  🇺🇸 Johns Hopkins University, Baltimore, MD

  Frances J. Northington, MD

  TR&D 3

  neurologic imaging
• Rapid three-dimensional simultaneous knee multi-relaxation mapping

  🇺🇸 Harvard Medical School, Boston, MA

  Fang Liu, PhD

  TR&D 1

  musculoskeletal imaging
• Advanced next generation radio frequency coils for magnetic resonance imaging

  🇺🇸 Advanced Imaging Research, Inc, Cleveland, OH

  Ravi Srinivasan

  TR&D 2

  neurologic imaging
• Diffusion MRI as an in vivo microscope for brain structure and function

  🇨🇭 University of Lausanne, Switzerland

  Ileana Jelescu, PhD

  TR&D 3

  neurologic imaging
• Improved detection of cerebral metastases using a novel T1 relaxation-enhanced steady-state (T1RESS) MRI Technique

  🇺🇸 NorthShore University HealthSystem, Evanston, IL

  Robert R. Edelman, MD

  TR&D 1

  neurologic imaging, oncologic imaging
• Noninvasive assessment of portal hypertension and hepatic interstitial pressure with advanced magnetic resonance elastography

  🇺🇸 Mayo Clinic, Rochester, MN

  Meng Yin, PhD

  TR&D 1

  abdominal imaging
• Real-time MRI-guided adaptive radiotherapy of unresectable pancreatic cancer

  🇺🇸 Memorial Sloan Kettering Cancer Center, New York, NY

  Ricardo Otazo, PhD

  TR&D 1, TR&D 2

  oncologic imaging
• From 3D electron microscopy tissue model to pathology specific multidimensional diffusion MRI

  🇫🇮 University of Eastern Finland, Kuopio, Finland

  Alejandra Sierra, PhD

  TR&D 3

  neurologic imaging
• Characterization of whole brain demyelination and axon damage using high-resolution magnetic resonance imaging

  🇺🇸 Indiana University, Bloomington, IN

  Nian Wang, PhD

  TR&D 3

  neurologic imaging
• In vivo insights on small vessel changes with age using USPIO-enhanced MRI

  🇺🇸 Wayne State University, Detroit, MI
  🇺🇸 NYU Langone Health, New York, NY

  Mark E. Haacke, PhD; Yulin Ge, MD

  TR&D 1, TR&D 2

  neurologic imaging
• Effective medium theory for multi-dimensional diffusion MRI

  🇩🇰 Aarhus University, Denmark

  Sune Jespersen, PhD

  TR&D 3

  neurologic imaging
• A 3D multimodal micron-scale human brain atlas bridging single cell data, neuropathology, and neuroradiology

  🇺🇸 Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

  Partha P. Mitra, PhD

  TR&D 3

  neurologic imaging
• Transcranial photobiomodulation for alzheimer’s disease

  🇺🇸 NYU Langone Health, New York, NY

  Dan V. Iosifescu, MD

  TR&D 2

  neurologic imaging
• Advanced methods and applications for multinuclear MRI

  🇦🇺 University of Queensland, Brisbane, Australia
  🇺🇸 NYU Langone Health, New York, NY

  Martijn Cloos, PhD; Guillaume Madelin, PhD

  TR&D 1, TR&D 2

  musculoskeletal imaging
• Physics-driven and data-driven quantitative knee joint mapping

  🇺🇸 NYU Langone Health, New York, NY

  Ravinder Regatte, PhD; Marcelo Zibetti, PhD

  TR&D 1, TR&D 2

  musculoskeletal imaging
• End-to-end deep learning image reconstruction and pathology detection

  🇩🇪 Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

  Florian Knoll, PhD

  TR&D 1

  musculoskeletal imaging
• Genomic and imaging markers to understand and predict progression of joint damage after injury

  🇺🇸 NYU Langone Health, New York, NY

  Amparo Ruiz, PhD; Thorsten Kirsch, PhD

  TR&D 1

  musculoskeletal imaging
• Imaging of breast cancer: advances in image acquisition and interpretation

  🇺🇸 Weill Cornell Medicine, New York, NY
  🇺🇸 NYU Langone Health, New York, NY

  Sungheon Gene Kim, PhD; Linda Moy, MD

  TR&D 1

  oncologic imaging
• Ultrasound-based sensors for the fusion and motion correction of MRI and PET/CT data

  🇺🇸 Brigham and Women’s Hospital, Boston, MA

  Bruno Madore, PhD

  TR&D 1, TR&D 2

  oncologic imaging
• New-generation oncological MRI (New-OncoMRI): development, validation, and application

  🇪🇸 Vall D’Hebron Institute of Oncology (VHIO), Spain

  Francesco Grussu, PhD

  TR&D 3

  oncologic imaging
• Advanced diffusion imaging for management of renal cancer: oncologic control and renal functional reserve

  🇺🇸 NYU Langone Health, New York, NY

  Eric Sigmund, PhD

  TR&D 1, TR&D 3

  oncologic imaging
• Quantitative magnetic resonance biopsies: exploiting signal asymmetries for next-generation noninvasive biomarker mapping

  🇨🇭 University of Bern, Switzerland

  Jessica Bastiaansen, PhD

  TR&D 1, TR&D 3

  oncologic imaging
• Future imaging hardware and software platforms

  🇩🇪 Siemens Healthineers, Erlangen, Germany

  Donald Hardie, PhD; Himanshu Bhat, PhD

  TR&D 1, TR&D 2, TR&D 3

  industry partnership
• Artificial intelligence for automated risk assessment from high-field and low-field MR images

  🇺🇸 Siemens Healthineers, Princeton, NJ

  Dorin Comaniciu, PhD

  TR&D 1, TR&D 2, TR&D 3

  industry partnership
• Imaging methods and applications at 0.064 T

  🇺🇸 Hyperfine, Inc., Guilford, CT

  Megan Poorman, PhD

  TR&D 1, TR&D 2, TR&D 3

  industry partnership
• New use cases for low-field MRI systems

  🇨🇭 Multiwave Technologies AG, Geneva, Switzerland

  Panos Antonakakis, PhD

  TR&D 1, TR&D 2

  industry partnership
• MR-guided radiation therapy: motion monitoring and tissue bioeffects

  🇸🇪 Elekta, Stockholm, Sweden
  🇳🇱 Philips Healthcare, Best, Netherlands
  🇺🇸 Philips Healthcare, Andover, MA

  John Christodouleas, MD; E. Brian Welch, PhD

  TR&D 1, TR&D 2

  industry partnership
• Rapid robust pediatric MRI

  🇺🇸 Stanford University, Palo Alto, CA
  🇺🇸 University of California at Berkeley, Berkeley, CA

  Shreyas Vasanawala, MD, PhD; Miki Lustig, PhD

  TR&D 1

  musculoskeletal, neurologic, oncologic, and cardiovascular imaging
• Cloud MR: an open-source software framework to democratize MRI training and research

  🇺🇸 NYU Langone Health, New York, NY

  Riccardo Lattanzi, PhD

  TR&D 1, T&D
• Diabetes, RAGE/DIAPH1 and myocardial infarction

  🇺🇸 NYU Langone Health, New York, NY

  Ravichandran Ramasamy, PhD

  TR&D 2

  cadiovascular imaging

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Active Collaborative Projects

Collaborative projects sustained during our NCBIB’s current funding period.

Contact

To inquire about establishing a Collaborative Project, write Kayse Lewis, Collaborative and Service Projects coordinator, at Kayse.Lewis@nyulangone.org.