Ryan Brown

Ryan Brown, PhD
Assistant Professor
Key Personnel
Room 401 660 First Avenue New York, NY 10016   www.ryanjbrown.com
Educational Details: 

2002, Bachelor of Science in Electrical Engineering, Arizona State University

2008, Doctor of Philosophy in Physiology, Biophysics and Systems Biology, Cornell University – Weill Graduate School of Medical Sciences

Research Interest: 
  1. Hardware design for optimal phosphorus & sodium MRI
  2. Metabolic evaluation in the skeletal muscle using phosphorus MRI
  3. Tumor monitoring in breast cancer patients undergoing NACT using sodium MRI
  4. High-field (7 Tesla) coil design
  5. Pilot tone navigation to track respiratory motion
Selected Publications: 
  1. R. Brown, O. Khegai, P. Parasoglou. “Magnetic Resonance Imaging of Phosphocreatine and Determination of BOLD Kinetics in the Lower Extremities with a Dual-Frequency Coil Array,” Scientific Reports, 2016; 6: 30568.
  2. R. Brown, K. Lakshmanan, G. Madelin, P. Parasoglou. “A Nested Phosphorus and Proton Coil Array for Brain MR Imaging and Spectroscopy,” NeuroImage, 2016 Jan; 124: 602-611.
  3. R. Brown, K. Lakshmanan, G. Madelin, L. Alon, G. Chang, D.K. Sodickson, R.R. Regatte, G.C. Wiggins. “A Flexible Nested Dual-Nuclei Sodium and Proton Coil Array with Wideband Matching for Knee Cartilage MRI at 3 Tesla,” available in early view in Magnetic Resonance in Medicine, 2015.
  4. M.V. Vaidya, C.M. Collins, D.K. Sodickson, R. Brown, G.C. Wiggins, R. Lattanzi. “Dependence of B1+ and B1- Field Patterns on the Electrical Properties of the Sample and the Static Magnetic Field Strength,” Concepts in Magnetic Resonance, 2016:46(1):25-40.
  5. L. Alon, C.M. Deniz, G. Carluccio, R. Brown, D.K. Sodickson, C.M. Collins. “Effects of Anatomical Differences on Electromagnetic Fields, SAR, and Temperature Change,” Concepts in Magnetic Resonance Part B, 2016:46(1):8-18.
  6. G.C. Wiggins, R. Brown, K. Lakshmanan. “High Performance RF Coils for Sodium MRI: Brain and Musculoskeletal Applications,” NMR in Biomedicine, 2015:29(2):96-106.
  7. C.M. Deniz, L. Alon, R. Brown, Y. Zhu. “Subject and Resource Specific Monitoring and Proactive Management of Parallel RF Transmission,” Magnetic Resonance in Medicine, 2015:76(1):20-31.
  8. Q. Duan, J. Duyn, N. Gudino, J. de Zwart, P. van Gelderen, D.K. Sodickson, R. Brown. “Characterization of a dielectric phantom for high-field MRI applications,” Medical Physics, 2014 Oct;41(10): 102303.
  9. R. Brown, P. Storey, C. Geppert, K. McGorty, A-P Klautau Leite, J.S. Babb, D.K. Sodickson, G.C. Wiggins, L. Moy. “Breast MRI at 7 Tesla with a Bilateral Coil and Robust Fat Suppression," J Magnetic Resonance Imaging, 2014 Mar; 39(3): 540-549.
  10. R. Brown, C.M. Deniz, B. Zhang, C. Stefanescu, G. Chang, D.K. Sodickson, G.C. Wiggins. "Design and Application of Combined 8 Channel Transmit and 10 channel Receive Arrays and RF Shimming for 7 Tesla Shoulder MRI," Investigative Radiology, 2014 Jan; 49(1): 35-47.
  11. G. Chang, S. Honig, R. Brown, C.M. Deniz, R.R. Regatte, C. Rajapakse. "Finite Element Analysis Applied to 3-T MR Imaging of Proximal Femur Microarchitecture: Lower Bone Strength in Patients with Fragility Fractures Compared with Control Subjects," Radiology, 2014 Aug; 272(2):464-74.
  12. G. Chang, C.M. Deniz, S. Honig, C. Rajapakse, R.R. Regatte, Y. Zhu, D.K. Sodickson, R. Brown. "MRI of the Hip at 7 Tesla: Feasibility of Bone Microarchitecture, High-Resolution Cartilage, and Clinical Imaging," J Magnetic Resonance Imaging, 2014 Jun;39(6):1384-93.
  13. G. Chang, C.M. Deniz, C. Rajapakse, R.R. Regatte, S. Honig, R. Brown. "Feasibility of three-dimensional MRI of Proximal Femur Microarchitecture at 3 Tesla using 26 Receive Elements without and with Parallel Imaging," J Magnetic Resonance Imaging, 2014 Jul;40(1):229-38.
  14. R. Brown, P. Storey, C. Geppert, K. McGorty, A-P Klautau Leite, J.S. Babb, D.K. Sodickson, G.C. Wiggins, L. Moy. “7 Tesla Breast MRI: Image Evaluation and Comparison to 3 Tesla," European Radiology, 2013 Nov; 23(11): 2969-2978.
  15. R. Brown, G. Madelin, R. Lattanzi, G. Chang, R.R. Regatte, D.K. Sodickson, G.C. Wiggins. “Design of an Eight Channel Nested Sodium and Proton Coil for 7 Tesla Knee Imaging,” Magnetic Resonance in Medicine, 2013 Jul;70(1):259-68.
  16. C.M. Deniz, R. Brown, R. Lattanzi, L. Alon, D. Sodickson, Y. Zhu. "Maximum Efficiency RF Shimming: Theory and Initial Application on Hip Imaging at 7 Tesla," Magnetic Resonance in Medicine, 2013 May;69(5):1379-88.
  17. L. Alon, C.M. Deniz, R. Brown, D. Sodickson, Y. Zhu, “A Method for In-Situ Characterization of RF Heating in Parallel Transmit MRI,” Magnetic Resonance in Medicine, 2013 May;69(5):1457-65.
  18. L. Fleysher, N. Oesingmann, R. Brown, D. Sodickson, G. Wiggins, M. Inglese. “Non-invasive Quantification of Intracellular Sodium in Human Brain using Ultra-High Field MRI,” NMR in Biomedicine, 2013 Jan;26(1):9-19.
  19. C.M. Deniz, L. Alon, R. Brown, D. Sodickson, Y. Zhu. “Specific Absorption Rate Benefits of Including Measured Electric Field Interactions in Parallel Excitation Pulse Design,” Magnetic Resonance in Medicine, 2012 Jan;67(1):164-74.
  20. Y. Zhu, L. Alon, C. Deniz, R. Brown, D. Sodickson. “System and SAR Characterization in Parallel RF Transmission,” Magnetic Resonance in Medicine, 2012 May;67(5):1367-78.
  21. R. Brown, C. Karmonik, G. Brunner, A. Lumsden, C. Ballantyne, S. Johnson, Y. Wang, J. Morrisett. "Simultaneous Bilateral Magnetic Resonance Imaging of the Femoral Arteries in Peripheral Arterial Disease Patients," J Magnetic Resonance Imaging, 2011 Jul;34(1):150-6.
  22. R. Brown, T.D. Nguyen, P. Spincemaille, M. Cham, G. Choi, P.A. Winchester, M.R. Prince, Y. Wang. “Effect of Blood Flow on Double Inversion Recovery Vessel Wall MRI of the Peripheral Arteries: Quantitation With T2 Mapping and Comparison With Flow-Insensitive T2-Prepared Inversion Recovery Imaging,” Magnetic Resonance in Medicine, 2010 Mar;63(3):736-44.
  23. R. Brown, T.D. Nguyen, P. Spincemaille, M.R. Prince, Y. Wang. “In vivo quantification of femoral-popliteal compression during isometric thigh contraction: Assessment using MR angiography,” J Magnetic Resonance Imaging, 2009 May;29(5):1116-24.
  24. L. de Rochefort, R. Brown, M.R. Prince, Y. Wang. “Quantitative Susceptibility Imaging using Piece-Wise Constant Regularized Inversion of the Magnetic Field,” Magnetic Resonance in Medicine, 2008 Oct;60(4):1003-9.
  25. L. de Rochefort, T. Nguyen, R. Brown, G. Choi, J. Weinsaft, M.R. Prince, Y. Wang. “In vivo quantification of contrast agent concentration using the induced magnetic field for time-resolved arterial input function measurement with MRI,” Medical Physics, 2008 Dec;35(12):5328-39.
  26. R. Brown, Y. Wang, P. Spincemaille, R.F. Lee. “On the Noise Correlation Matrix for Multiple RF Coils,” Magnetic Resonance in Medicine, 2007 Aug;58(2):218-24.
  27. R. Brown, M.R. Prince, H. Ersoy, M. Dooley, A. Mareyam, B. Ho,  K. Mohajer, Y. Wang. “Design of a Birdcage Array for Lower Extremity Angiography,” J Magnetic Resonance Imaging, 2007 Sep;26(3):589-97.
  28. P. Spincemaille, R. Brown, Y. Xian, Y. Wang. “Optimal Coil Design: The Two Coil Case,” Magnetic Resonance Imaging, 2007 Jun;25(5):671-7.
  29. R. Brown, A. Mareyam, E. Reid, Y. Wang. “Novel RF Coil Geometry for Lower Extremity Imaging,” Magnetic Resonance in Medicine, 2004 Mar;51(3):635-9.


Additional Information: 


1. R. Brown, Y. Wang. "Dual Lower Extremity MRI Coil Array," US Patent, 12/548,172, 2009. 

2. G.C. Wiggins, R. Brown. "Multi-Nuclei MRI Coil," US Patent. 13/866,728, 2013.

3. R. Brown, M.A. Cloos, G.C. Wiggins. “Split-Symmetric Parallel Transmission System,” US Provisional Patent Application, 61/983,933, 2014.


2011 – Present                         Ad Hoc Reviewer    Magnetic Resonance in Medicine

2012 – Present                         Ad Hoc Reviewer    European Radiology

2013 – Present                         Ad Hoc Reviewer    Journal of Magnetic Resonance Imaging

2014 – Present                         Ad Hoc Reviewer    IEEE Transactions on Biomedical Engineering

2014 – Present                         Ad Hoc Reviewer    PLoS One

2014                                            Grant Reviewer       Mitacs Elevate

2014, 2015, 2016                    Abstract Reviewer  International Society for Magnetic Resonance in Medicine

2015                                            Ad Hoc Reviewer    NMR in Biomedicine

2015                                          Ad Hoc Reviewer    Journal of Magnetic Resonance


2011 – Present, Laboratory Instructor for Practical MRI I (NYU Sackler graduate course)


2011 – Present, Coil Safety Committee, NYU Center for Biomedical Imaging

2013 – Present, NYU Fossil Fuel Divestment



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Philanthropic Support

We gratefully acknowledge generous support for radiology research at NYU Langone Medical Center from:
• The Big George Foundation
• Raymond and Beverly Sackler
• Bernard and Irene Schwartz

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