Christopher M. Collins

Christopher M. Collins, PhD
Professor of Radiology
Function: 
Principal Investigator
Affiliation: 
CAI²R
Phone: 
(212)263-3322
Fax: 
+1-212-263-7541
Address: 
4th Floor, Room 403  660 First Avenue New York, NY 10016
Educational Details: 

1993 BS in Engineering Science from The Pennsylvania State University

1994 MS in Biomedical Engineering from The University of Pennsylvania

1999 PhD in Biomedical Engineering from The University of Pennsylvania

Research Interest: 

To accomplish Magnetic Resonance Imaging (MRI) we apply a variety of magnetic fields to the human body. These fields interact with human tissues in a variety of ways, resulting not only in the signal needed to create images, but in random fluctuations (or noise) and distortions (or artifacts) degrading these images, and in potential physiological effects. To maximize the performance and safety of MRI it is important to have a thorough understanding of the behavior of the applied fields throughout the human body. Much of my research is devoted to the development, validation, and application of computational tools to characterize field/tissue interactions in MRI and their effects on image integrity and patient safety with the ultimate goal of engineering better and safer MRI systems and techniques for the future. As the technology of MRI develops, this requires consideration of static, audiofrequency (gradient), and radiofrequency magnetic fields from an increasing number of sources (coils), as well as increasingly complex combinations of the signal and noise induced in multiple receive coils throughout time for reconstruction of images. 

Selected Publications: 

1.    Li S, Dardzinski BJ, Collins CM, Yang QX, Smith MB:  “Three-Dimensional Mapping of the Static Magnetic Field Inside the Human Head.”  Magn. Reson. Med., 36:705-714, 1996. PMID: 8916021

2.    Li S, Collins CM, Dardzinski BJ, Chin C-L, Smith MB:  “A Method to Create an Optimum Current Distribution and Homogeneous B1 Field  for Elliptical Birdcage Coils.” Magn. Reson. Med., 37:600-608, 1997. PMID: 9094083

3.    Collins CM, Li S, Yang QX, Smith MB:  “A Method for Accurate Calculation of B1 Fields in Three Dimensions:  Effects of Shield Geometry on Field Strength and Homogeneity in the Birdcage Coil.”  J. Magn. Reson., 125:233-241, 1997. 

4.    Dardzinski BJ, Li S, Collins CM, Williams GD, Smith MB:  “A birdcage coil tuned by RF shielding for application at 9.4 T.”  J. Magn. Reson., 131(1):32-8, 1998. PMID: 9533903

5.    Strilka RJ, Li S, Martin JT, Collins CM, Smith MB:  “A numerical study of radiofrequency deposition in a spherical phantom using surface coils.”  Magn. Reson. Imag. 16(7):787-798, 1998. PMID: 9811144

6.    Collins CM, Li S, Smith MB:  “SAR and B1 Field Distributions in a Heterogeneous Human Head Model within a Birdcage Coil.” Magn. Reson. Med. 40:847-856, 1998. PMID: 9840829

7.    Collins CM and Smith MB. “Signal-to-Noise Ratio and Absorbed Power as Functions of Main Magnetic Field Strength and Definition of “90” RF Pulse for the Head in the Birdcage Coil.” Magn. Reson. Med. 45:684-691, 2001. PMID: 11283997

8.    Collins CM and Smith MB. “Calculations of B1 Distribution, SNR, and SAR for a Surface Coil Against an Anatomically-accurate Human Body Model.” Magn. Reson. Med., 45:692-699, 2001. PMID: 11283998

9.    Alecci M, Collins CM, Smith MB, and Jezzard P: “Radio frequency magnetic field mapping of a 3 Tesla birdcage coil: experimental and theoretical dependence on sample properties.” Magn. Reson. Med., 46:379-385, 2001. PMID: 11477643

10.    Smith HE, Mosher TJ, Dardzinski BJ, Collins BG, Collins CM, Yang QX, Schmithorst VJ, Smith MB: “Spatial Variation in Cartilage T2 of the Knee.” J. Magn. Reson. Imag., 14:50-55, 2001. PMID: 11436214

11.    Vaughan JT, Garwood M, Collins CM, Liu W, DelaBarre L, Kim SG, Adriany G, Andersen P, Merkle H,  Goebel R, Smith MB, and Ugurbil K: “7T vs. 4T:  RF Power, Homogeneity, and Signal-to-Noise Comparison in Head Images.”  Magn. Reson. Med., 46:24-30, 2001. PMID: 11443707

12.    Collins CM, Yang QX, Wang JH, Zhu X-H, Adriany G, Michaeli S, Vaughan JT, Zhang X, Liu H, Anderson P, Ugurbil K, Smith MB, and Chen W. “Different Excitation and Reception Distributions with a Single-Loop Transmit-Receive Surface Coil Near a Head-Sized Spherical Phantom at 300 MHz.” Magn. Reson. Med., 47:1026-1028, 2002. PMID: 11979585

13.    Yang QX, Wang JH, Collins CM, Smith MB, Zhang X, Liu H, Michaeli S, Zhu X-H, Adriany G, Vaughan JT, Anderson P, Ugurbil K, Chen W. “Analysis of Wave Behavior in Dielectric Samples at High Field,”  Magn. Reson. Med., 47:982-989, 2002. PMID: 11979578

14.    Chin CL, Collins CM, Li S, Dardzinski BJ, Smith MB. “BirdcageBuilder: Design of Specified-Geometry Birdcage Coils with Desired Current Pattern and Resonant Frequency, Concepts in Magn. Reson. B (Magn. Reson. Eng.) 15(2):156-163, June 2002. NIHMSID 377779

15.    Wang JH, Yang QX, Collins CM, Smith MB, Zhang X, Liu H, Zhu X-H, Adriany G, Ugurbil K, Chen W “Polarization of the RF Field in a Human Head at High Field: a Study with a Quadrature Surface Coil at 7.0 Tesla.”  Magn. Reson. Med., 48(2):362-369, August 2002. PMID: 12210945

16.    Collins CM, Yang B, Yang QX, and Smith MB. “Numerical Calculations of the Static Magnetic Field in Three-Dimensional Multi-Tissue Models of the Human Head.” Magn. Reson. Imag., 20:413-424, 2002. PMID: 12206867

17.    Alecci M, Collins CM, Wilson J, Liu W, Smith MB, Jezzard P, “Theoretical and Experimental Evaluation of Detached Endcaps for 3T Birdcage Coils.”  Magn. Reson. Med., 49:363-370, 2003. PMID: 12541257

18.    Beck B, Plant DH, Grant SC, Thelwall PE, Silver X, Mareci TH, Benveniste H, Smith M, Collins C, Crozier S. Blackband SJ:  Progress in High Field MRI at the University of Florida.  Magn. Reson. Materials in Physics, Biology and Medicine 13:152-157, 2002. NIHMSID 377783

19.    Collins CM and Smith MB, “Spatial resolution of numerical models of man and calculated specific absorption rate using the FDTD method: a study at 64 MHz in a magnetic resonance imaging coil.” J. Magn. Reson. Imag., 18:383-388, 2003. PMID: 12938138

20.    Liu W, Collins CM, Delp PJ, and Smith MB, “Effects of end-ring/shield configuration on homogeneity and signal-to-noise ratio in a birdcage-type coil loaded with a human head.” Magn. Reson. Med., 51:217-221, 2004. PMID: 14705065

21.    Mosher TJ, Collins CM, Smith HE, Moser LE, Sivarajah RT, Dardzinski BJ, and Smith MB. “Effect of gender on in vivo cartilage magnetic resonance imaging T2 mapping.” J. Magn. Reson. Imag., 19:323-328, 2004. PMID: 14994301

22.    Collins CM, Liu W, Wang JH, Gruetter R, Vaughan JT, Ugurbil K, and Smith MB, “Temperature and SAR calculations for a human head within volume and surface coils at 64 and 300 MHz.” J. Magn. Reson. Imag., 19:650-656, 2004. PMID: 15112317

23.    Yang QX, Wang J, Collins CM, Smith MB, Zhang X, Ugurbil K, and Chen W, “Phantom Design Method for High-Field MRI Human Systems.” Magn. Reson. Med., 52:1016-1020, 2004. PMID: 15508165

24.    Collins CM, Smith MB, and Turner RW, “Model of local temperature changes in brain upon functional activation.” J. Appl. Physiol. 97:2051-2055, 2004. PMID: 15322067

25.    Collins CM, Liu W, Schreiber W, Yang QX, and Smith MB. Central Brightening Due to Constructive Interference With, Without, and Despite Dielectric Resonance. J. Magn. Reson. Imag. 21:192–196, 2005. PMID: 15666397

26.    Lazovic J, Stokovic DS, Collins CM, Yang QX, Vaughan JT, Smith MB. Hexagonal zero-mode TEM coil: a single-channel coil design for imaging of multiple small animals. Magn. Reson. Med., 53:1150-1157, 2005. PMID: 15844165

27.    Lazovic J, Wrzos HF, Yang QX, Collins CM, Smith MB, Norgren R, Matyas K, Ouyang A. Regional activation in the rat brain during visceral stimulation detected by c-FOS expression and fMRI. Neurogastroenterology and Motility 17:548-556, 2005. PMID: 16078944

28.    Liu W, Collins CM, Smith MB. Calculations of B1 distribution, Specific Energy Absorption Rate, and Intrinsic Signal-to-Noise Ratio for a Body-size Birdcage Coil Loaded with Different Human Subjects at 64 and 128 MHz. Appl. Magn. Reson. 29:5-18, 2005. (invited) NIHMSID 377781

29.    Sun L, Collins CM, Schiano JL, Smith MB, Smith NB. Adaptive real-time closed-loop temperature control for ultrasound hyperthermia using magnetic resonance thermometry. Concepts Magn. Reson. 27B:51-63, 2005. NIHMSID 377786

30.    Maril N, Collins CM, Greenman RL, Lenkinski RE. Strategies for shimming the breast. Magn. Reson. Med. 54:1139-1145, 2005. PMID: 16217775

31.    Van de Moortele P-F, Akgun C, Adriany G, Moeller S, Ritter J, Collins CM, Smith MB, Vaughan JT, Ugurbil K. B1 interferences and spatial phase patterns at 7 tesla with a head transceiver array coil. Magn. Reson. Med. 54:1503-1518, 2005. PMID: 16270333

32.    Collins CM, Liu W, Swift BJ, Smith MB. Combination of optimized transmit arrays and some parallel imaging reconstruction methods can yield homogeneous images at very high frequencies. Magn. Reson. Med. 54:1327-1332, 2005. PMID: 16270331

33.    Mosher TJ, Smith HE, Collins CM, Liu Y, Hancy J, Dardzinski BJ, Smith MB. Change in knee cartilage T2 after running: a feasibility study. Radiology 234:245-249, 2005.

34.    Mao W, Chronik BA, Feldman RE, Smith MB, Collins CM. Consideration of magnetically-induced and conservative electric fields within a loaded gradient coil. Magn. Reson. Med. 55:1424-1432, 2006. (June) PMID: 16680728

35.    Mao W, Smith MB, and Collins CM. Exploring the Limits of RF Shimming for High-Field MRI of the Human Head. Magn Reson Med 56:918-922, 2006. (October) PMID: 16958070

36.    Al-Bataineh OM, Collins CM, Park E-J, Lee H, and Smith NB. MR thermometry characterization of a hyperthermia ultrasound array designed using the k-space computational method. BioMedical Engineering OnLine 5:56, 2006. (October) PMCID: PMC1635715

37.    Liu W, Zhang S, Collins CM, Wang J, Smith MB. Comparison of four different shields for birdcage-type coils with experiments and numerical calculations. Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering Volume 29B, Issue 4, p 176-184, 2006. (October) NIHMSID 377788

38.    Collins CM, Wang Z, Mao W, Fang J, Liu W, Smith MB. Array-optimized Composite Pulses for Excellent Whole-Brain Homogeneity in High Field MRI. Magn Reson Med 57:470-474, 2007. (March) PMID: 17326169

39.    Mao W, Wang Z, Smith MB, Collins CM. Calculation of SAR for Transmit Coil Arrays. Concepts in Magnetic Resonance 31B:127-131, 2007. (April) 

40.    Meadowcroft MD, Zhang S, Liu W, Park BS, Connor JR, Collins CM, Smith MB, Yang QX. Direct Magnetic Resonance Imaging of Histological Tissue Samples at 3.0T. Magn Reson Med 57:835–841, 2007. (May) PMID: 17457873

41.    Wang Z, Lin JC, Mao W, Liu W, Smith MB, Collins CM. SAR and Temperature: Simulations and Comparison to Regulatory Limits for MRI. J Magn Reson Imag 26:437–441, 2007. (August) PMID: 17654736

42.    Wang Z, Collins CM. Consideration of Physiological Response in Numerical Models of Temperature During MRI of the Human Head. J Magn Reson Imaging 28:1303–1308, 2008. (November) PMCID: PMC2597208

43.    Park BS, Webb AG, Collins CM. “A method to separate conservative and magnetically-induced electric fields in calculations for MRI and MRS in electrically-small samples.” J Magn Reson 199(2):233-237, 2009. (August) PMCID: PMC2722947

44.    Collins CM. “Numerical Field Calculations Considering the Human Subject for Engineering and Safety Assurance in MRI.” NMR Biomed 2009;22(9):919-926. (November) PMCID: PMC2836719 (invited review article)

45.    Park BS, Neuberger T, Webb AG, Bigler DC, Collins CM. Faraday shields within a solenoidal coil to reduce sample heating: numerical comparison of designs and experimental verification. J Magn Reson 2010;202:72-77. (January) PMCID: PMC2818242

46.    Oh S, Webb AG, Neuberger T, Park BS, Collins CM. “Experimental and Numerical Assessment of MRI-Induced Temperature Change and SAR Distributions in Phantoms and In Vivo.” Magn Reson Med 2010;63:218-223. (January) PMCID: PMC2836721

47.    Webb AG, Collins CM, Versluis MJ, Kan HE, Smith NB. MRI and localized proton spectroscopy in human leg muscle at 7 tesla using longitudinal traveling waves. Magn Reson Med 2010;63:297-302. (February) PMC2846515

48.    Webb AG, Collins CM. Parallel Transmit and Receive Technology in High-Field Magnetic Resonance Neuroimaging. Int J Imaging Syst Technol 2010;23:2-13. (March) PMCID: PMC2846515

49.    Avdievich NI, Oh S, Hetherington HP, Collins CM. Improved homogeneity of the transmit field by simultaneous transmission with phased array and volume coil. J Magn Reson Imaging 2010;32:476-481. (August) PMCID: PMC2925674

50.    Wang Z, Collins CM. Effect of RF pulse sequence on temperature elevation for a given time-average SAR. Concepts Magn Reson Part B (Magn Reson Engineering) 2010;37B:215-219 PMCID: PMC2992348 

51.    Vossen M, Teeuwisse W, Reijnierse M, Collins CM, Smith NB, Webb AG. A radiofrequency coil configuration for imaging the human vertebral column at 7 tesla. J Magn Reson, 2011;208:291-297. NIHMSID 377791

52.    Yang QX, Wang J, Wang J, Collins CM, Wang C, Smith MB. Reducing SAR and enhancing cerebral signal-to-noise ratio with high permittivity padding at 3 T. Magn Reson Med, 2011;65:358-362. PMID: 21121001 PMC3073646

53.    Collins CM and Wang Z. Calculation of radiofrequency electromagnetic fields and their effects in MRI of human subjects. Magn Reson Med, 2011;65:1470-1482. (Invited Review Article) (May) PMC3078983

54.    Roopnariane CA, Ryu Y-C, Tofighi M-R, Miller PA, Oh S, Wang J, Park BS, Ansel L, Lieu CA, Subramanian T, Yang QX, Collins CM. Quadrature RF coil for in vivo brain MRI of a macaque monkey in a stereotaxic head frame. Concepts Magn Reson B 2012;41B(1)22-27. NIHMSID 359246

55.    Liu W, Kao C-P, Collins CM, Smith MB, Yang QX. On consideration of radiated power in RF field simulations for MRI. Magn Reson Med, published online April 3, 2012. NIHMSID 360584

Sponsors

Latest Updates

08/13/2018 - 14:41
08/01/2018 - 15:48
07/16/2018 - 13:43

Philanthropic Support

We gratefully acknowledge generous support for radiology research at NYU Langone Medical Center from:
 
• The Big George Foundation
• Raymond and Beverly Sackler
• Bernard and Irene Schwartz

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