Overview

A Biomedical Technology Resource Center

We are a Biomedical Technology Resource Center (BTRC) funded by the National Institute of Biomedical Imaging and Bioengineering since 2014.

There are two dozen such Centers in the United States, each with a special focus and mission. Here’s how the NIH describes them:

These Centers create critical and unique technology and methods at the forefront of their respective fields and apply them to a broad range of basic, translational and clinical research. This occurs through a synergistic interaction of technical and biomedical expertise, both within the Centers and in intensive collaborations with other leading laboratories. Scientists at these Centers ensure that NIH-funded biomedical research projects may gain access to the newest and most advanced technologies, techniques, and methodologies.


Our Mission

The Center for Advanced Imaging Innovation and Research (CAI2R) pursues a mission of bringing people together to create new ways of seeing.

We work to create new paradigms for the acquisition, reconstruction, and interpretation of biomedical images. We implement new models of interdisciplinary collaboration in order to rapidly translate new technological developments into clinical practice. We discover new knowledge, invent new technologies, and develop new devices to advance medical imaging and improve human health.


The Changing World of Biomedical Imaging

Our center is at the forefront of a sea change in biomedical imaging. Tasks that were once the sole domain of meticulously-engineered imaging hardware are now beginning to be accomplished in software, increasingly informed by diverse arrays of inexpensive auxiliary sensors. Information once pursued through the laborious acquisition of carefully separated image datasets is now being derived from newly integrated, and richly quantitative, data streams.

The Rebirth of Medical Imaging

Below, a short overview of current trends in biomedical imaging delivered as keynote at the 2018 LDV Vision Summit by our Center's principal investigator Daniel Sodickson, MD, PhD.
 

 
Duration: 12 minutes. Source: LDV Vision Summit 2018 via Vimeo.

Imaging in a Changing World: The Scanners of the Future and the Future of Scanning

Below, a lecture about the latest technological advances in biomedical imaging given by Dr. Sodickson as a Radiology Grand Rounds seminar at Stanford University in December 2018.
 

 
Duration: 55 minutes. Source: Stanford University Radiology Grand Rounds .


Research Directions

Our Center is organized around the following four Technology Research and Development (TR&D) projects:

  1. Reimagining the Future of Scanning: Intelligent image acquisition, reconstruction, and analysis
  2. Unshackling the Scanners of the Future: Flexible, self-correcting, multi-sensor machines
  3. Enriching the Data Stream: MRI and PET in concert
  4. Revealing Microstructure: Biophysical modeling and validation for discovery and clinical care

In each of these projects, we aim at bringing about next-generation hardware and software technologies for medical imaging.

Having made great strides in developing rapid, continuous imaging data streams since the founding of our Center in 2014, we now aim at adding key new information to those streams, both from physics-driven microstructural modeling and from data-driven machine learning. After developing robust tools for image acquisition and reconstruction, we are focusing on extending the pipeline to image interpretation. We are investigating ways to use the results of human- or machine-derived evaluations of image content as feedback for the further improvement of acquisition strategies and sensor designs. We are also exploring new ways to guide therapy with continuously-acquired information about tissue bioeffects in order to close the loop between diagnostic sensing and therapeutic intervention.


Research Collaboration and Technology Dissemination

Our Center has an explicit translational focus, reflected in the day-to-day operation of TR&D projects as well as in the topics of Collaborative Projects (CPs) and Service Projects (SPs), aligned with three general areas of high public health impact: cancer, musculoskeletal disease, and neurologic disease.

In keeping with this translational emphasis, our Center is driven by an embedded collaboration model in which basic scientists, clinicians, and industry developers sit down together regularly at the scanners for interactive technology development and assessment. With early involvement of clinical stakeholders and industry partners, we aim at making CAI2R technologies widely available for the advancement of biomedical knowledge and for the benefit of patients and the physicians who care for them.

Sponsors

Latest Updates

11/12/2019 - 09:50
11/12/2019 - 09:49
11/12/2019 - 09:28

Philanthropic Support

We gratefully acknowledge generous support for radiology research at NYU Langone Health from:
 
• The Big George Foundation
• Raymond and Beverly Sackler
• Bernard and Irene Schwartz

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