Research Centers

Research Centers

Bernard and Irene Schwartz Center for Biomedical Imaging (CBI)

660 First Avenue, New York, NY, 10016

The CBI occupies approximately 20,000 square feet on several floors of the building, and various expansions are currently underway. The first floor includes scanner suites, patient preparation rooms, reception areas, and selected staff offices.

A fully equipped state of the art radio frequency engineering laboratory, which forms the physical core of the Raymond and Beverly Sackler Laboratories for Convergence of Biomedical, Physical, and Engineering Sciences, occupies 1,000 square feet on the second floor, directly adjacent to a clinical reading room, the offices of the Department of Radiology’s clinical neuroradiology section, and the office of a cadre of 50/50 clinical researchers who work closely with our basic imaging researchers. (The Sackler Laboratories provide support for investigators interested in cross-cutting projects which bring basic biophysics and technology development to bear in addressing high-impact problems in human health.)

Offices for faculty, staff, and research administrators occupy the fourth floor, along with two conference rooms and various common areas with shared business equipment. A machine shop staffed by a full-time dedicated machinist is located in the basement.

The approximately 70 staff housed in the Center (not including the clinical colleagues on the second floor) are comprised of principal investigators and their students and fellows, research coordinators who assist with human studies, administrative staff, and various core scientists and engineers who provide RF engineering and pulse programming support for Departmental projects and investigators.

Research MRI units:

• A 64-receive-channel Siemens Prisma 3 Tesla MR scanner with 2-channel parallel transmission capability
• A 64-receive-channel large-bore Siemens Skyra 3 Tesla scanner with 2-channel parallel transmission capability.
• A whole-body 7 Tesla scanner with 32 receiver channels and 8 integrated transmit channels. A custom-designed Analogic 32-channel parallel transmission system is also available for use with the 7T scanner.
• A 3 Tesla Siemens mMR combined MR-PET scanner capable of simultaneous and spatially co-registered MR and PET scanning. This scanner, together with an onsite cyclotron and radiochemistry laboratory currently under development, will serve as a collaborative resource.

RF Coil Arrays:

Numerous product-level and prototype radiofrequency coil arrays, ranging from 1 to 128 elements, are available for use with our research systems.

RF Test Equipment:

A full complement of RF test equipment is available in the RF laboratory space at the CBI, which also houses an automated router for precision coil array fabrication.

Computer Equipment:

Various high-performance multicore Windows servers are available in the CBI for computationally-intensive tasks of numerical simulation, image reconstruction, or image processing.

Machine Shop:

A fully-equipped machine shop, staffed by a full-time machinist employed by the NYU Department of Radiology, is located in the basement of 660 First Avenue, and is available for fabrication of RF coil formers, MR phantoms, and other research devices.

 

Skirball Institute of Biomolecular Medicine

550 First Avenue, New York, NY, 10016

The NYULMC Office of Collaborative Science (OCS), in partnership with the Department of Radiology, have established a Small Animal Imaging (SAI) core facility comprised of existing and newly installed imaging instruments (a 7 Tesla animal MR scanner, a micro-PET-CT, three IVIS Lumina Bioluminesence and Fluorescence scanners, two high frequency ultrasound Visualsonics scanners) located throughout the medical campus. These devices, together with several newly acquired animal irradiators for radiation oncology research are located throughout the medical campus within or outside the pathogenic barrier, nearby the various vivariums. Siting of some of these instruments outside the pathogenic barrier enables access and supports a broad range of investigators with new biomedical research projects not served by some of our existing animal scanners.

The entire core is directed by Dr. Wadghiri (Assistant Professor at the Department of Radiology) and a team of three full time staff with animal imaging expertise in the various imaging modalities available. It offers fee-for-service access for biomedical researchers to noninvasive and nonlethal three-dimensional imaging, whether for short-term evaluation of new animal models or for efficient longitudinal studies.

 

The Nathan S. Kline Institute for Psychiatric Research

140 Old Orangeburg Road, Orangeburg, NY 10962

The Nathan S. Kline Institute for Psychiatric Research (NKI) is a facility of the New York State Office of Mental Health that has earned a national and international reputation for its pioneering contributions in psychiatric research, especially in the areas of psychopharmacological treatments for schizophrenia and major mood disorders, and in the application of computer technology to mental health services. Since 1952, interdisciplinary teams of distinguished NKI scientists have applied their talents and expertise to study the etiology, treatment, prevention, and rehabilitation of severe and persistent mental illnesses.

The Center for Advanced Brain Imaging (CABI) at the Nathan Kline Institute (NKI) is a multi-disciplinary clinical diagnostic and research facility. The CABI supports brain research into numerous mental health related disorders including schizophrenia, dementia, central nervous system injury, memory deficits, substance abuse and drug therapies. Functional Magnetic Resonance Imaging (fMRI), Diffusion Tensor Imaging (DTI), Perfusion magnetic resonance imaging (pMRI), anatomical imaging and metabolite and neurotransmitter imaging are among the tools available for use in the Center. .

The facility, approximately 12,000 sq. ft. in size, is centered around the technology of Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS) and houses three state-of-the-art MR systems. An extensive image analysis center, machine and electronic shops and cognitive testing facilities are available in the Center.

The CABI is equipped with MRI compatible physiological monitoring and triggering equipment, and houses a full surgical suite and wet laboratory, as well as electronics shop and machining shop for instrument repair, coil building and MR support structure construction..

Research MRI units:

• A 1.5 Tesla MR scanner
• A 32-receive-channel 3 Tesla scanner.
• A 7 Tesla animal scanner.

 

Animal preclinical imaging systems

At the Skirball institute:

  • A 7 Tesla Micro-MRI (µ-MRI) Bruker Biospec system, 20-cm horizontal bore, superconducting magnet (Magnex Scientific, Abington UK) for mouse imaging.
  • An IVIS Lumina III XR (Perkin Elmer) bioluminescence/fluorescence optical imaging system is available as a fee-for-service shared instrument within the Skirball vivarium.
  • A Vevo 770 Visualsonics (Fujifilm) high frequency ultrasound biomicroscopy scanner is available as a fee-for-service shared instrument within the Skirball vivarium within the SPF barrier. This scanner is capable of imaging the adult mouse cardiovascular system, as well as the major abdominal organs.

At the NYU medical Science Building (adjacent to Skirball Institute building):

  • A state-of-the-art high resolution Siemens Inveon µ-PET/CT, equipped with a 64 block PET detector interfaced to 64 channels designed for efficient operation and high quantitative accuracy. The 12-cm bore size PET system (detector diameter: 16.1-cm, Transaxial active FOV: 10-cm, Axial FOV: 12.7-cm) supports mouse, rat and other in vivo small animal molecular imaging protocols.
  • A 7 Tesla Micro-MRI (µ-MRI) Bruker Biospec 70/30 MR system. Partially funded by a recent 2M$ NIH Shared instrumentation S10 award, the installation of this state-of-the-art MRI system will be completed in the Fall of 2015 and will enable a wider access from non-SPF vivarium to the NYU biomedical research community.
  • An IVIS Spectrum (Perkin Elmer) bioluminescence/fluorescence optical imaging system.
  • A Vevo 2100 Visualsonics (Fujifilm) high frequency ultrasound biomicroscopy scanner is available as a fee-for-service shared instrument outside the SPF barrier.

Sponsors

Latest Updates

Philanthropic Support

We gratefully acknowledge generous support for radiology research at NYU Langone Medical Center from:
 
• The Big George Foundation
• Raymond and Beverly Sackler
• Bernard and Irene Schwartz

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